Endocrine Abstracts

It is well accepted that sperm acrosome reaction occurs after the binding of the capacitated sperm to the egg zona-pellucida. This study describes a novel idea regarding the regulation of the sperm epidermal growth factor receptor (EGFR) under physiological conditions and the relevance to the acrosome reaction. Ouabain, a known Na/K ATPase blocker is present in our blood and in the female reproductive tract. We showed here for the first time that physiological concentrations (...